Association Between Adducin-1 G460W Variant and Blood Pressure in Swedes Is Dependent on Interaction With Body Mass Index and Gender
Author(s) -
Cristiano Fava,
Martina Montagnana,
P. Almgren,
L. Rosberg,
Gian Cesare Guidi,
G Berglund,
Olle Melander
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2007.04.007
Subject(s) - medicine , blood pressure , diastole , body mass index , population , cardiology , allele , polymorphism (computer science) , pulse pressure , endocrinology , genetics , gene , biology , environmental health
The W allele of the G460W polymorphism in the adducin-1 gene has been occasionally associated with increased blood pressure (BP). The aim of this study was to test whether the G460W variant is associated with BP levels and BP progression rate and whether G460W associations with BP are affected by sex, body mass index (BMI), or age.
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