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The W allele of the G460W polymorphism in the adducin-1 gene has been occasionally associated with increased blood pressure (BP). The aim of this study was to test whether the G460W variant is associated with BP levels and BP progression rate and whether G460W associations with BP are affected by sex, body mass index (BMI), or age.

Association Between Adducin-1 G460W Variant and Blood Pressure in Swedes Is Dependent on Interaction With Body Mass Index and Gender