Reduced Cardiovascular Reactivity to Stress but Not Feeding in Renin Enhancer Knockout Mice
Author(s) -
Kristy L. Jackson,
Geoffrey A. Head,
Billah Morris,
Jaye ChinDusting,
E. Anthony Jones,
L LAGRECA,
Dmitry N. Mayorov
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2007.02.010
Subject(s) - endocrinology , medicine , phenylephrine , renin–angiotensin system , knockout mouse , plasma renin activity , blood pressure , angiotensin ii , agonist , receptor
We have recently shown that the renin enhancer, a regulatory element of renin gene transcription, is important in the long-term control of basal blood pressure (BP). In this study, we examined whether the renin enhancer deficit alters the acute pressor response to emotional stress in mice.
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