An Additive Effect of Endothelial Nitric Oxide Synthase Gene Polymorphisms Contributes to the Severity of Atherosclerosis in Patients on Dialysis | Zendy

Belinda Spoto | Zendy; F. Benedetto | Zendy; A. Testa | Zendy; Giovanni Tripepi | Zendy; Francesca Mallamaci | Zendy; Renke Maas | Zendy; Rainer Boeger | Zendy; Carmine Zoccali | Zendy

Open Access

An Additive Effect of Endothelial Nitric Oxide Synthase Gene Polymorphisms Contributes to the Severity of Atherosclerosis in Patients on Dialysis

Author(s) -

Belinda Spoto,

F. Benedetto,

A. Testa,

Giovanni Tripepi,

Francesca Mallamaci,

Renke Maas,

Rainer Boeger,

Carmine Zoccali

Publication year - 2007

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2007.02.009

Subject(s) - medicine , allele , enos , genotype , population , gastroenterology , endocrinology , polymorphism (computer science) , cardiology , nitric oxide synthase , nitric oxide , genetics , gene , biology , environmental health

Reduced synthesis of nitric oxide (NO) is considered a major proatherogenic mechanism in patients with end-stage renal disease (ESRD), but genetic factors impinging on this mechanism have been little studied in this population.

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