Ferulic Acid Restores Endothelium-Dependent Vasodilation in Aortas of Spontaneously Hypertensive Rats | Zendy

Atsushi Suzuki | Zendy; Masaki Yamamoto | Zendy; Hidefumi Jokura | Zendy; Akira Fujii | Zendy; Ichiro Tokimitsu | Zendy; T. Hase | Zendy; Isao Saito | Zendy

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Ferulic Acid Restores Endothelium-Dependent Vasodilation in Aortas of Spontaneously Hypertensive Rats

Author(s) -

Atsushi Suzuki,

Masaki Yamamoto,

Hidefumi Jokura,

Akira Fujii,

Ichiro Tokimitsu,

T. Hase,

Isao Saito

Publication year - 2007

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2006.11.008

Subject(s) - superoxide , phenylephrine , vasodilation , endocrinology , nitric oxide , medicine , acetylcholine , endothelium , ferulic acid , vasoconstriction , spontaneously hypertensive rat , pharmacology , chemistry , biochemistry , blood pressure , enzyme

Ferulic acid (FA), a phytochemical constituent, has antihypertensive effects, but a detailed understanding of its effects on vascular function remains unclear. The vasoreactivity of FA was assessed using aortic rings isolated from normotensive Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHR).

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