Open AccessAdvanced Glycation End-Products and Arterial Stiffness in Hypertension
Author(s) -
Marie McNulty,
A MAHMUD,
J. Feely
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2006.08.009
Subject(s) - medicine , arterial stiffness , pulse wave velocity , glycation , cardiology , blood pressure , essential hypertension , advanced glycation end product , endocrinology , receptor
The formation of advanced glycation end-products is associated with arterial stiffness in experimental models and alagebrium (formerly known as ALT-711), an advanced glycation end-product cross-link breaker, has been shown to reduce arterial stiffness in elderly subjects.
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