Increased Pulse Pressure Amplification in Treated Hypertensive Subjects With Metabolic Syndrome
Author(s) -
Athanase D. Protogerou,
Jacques Blacher,
Myron Mavrikakis,
J. Lekakis,
Michel E. Safar
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2006.06.014
Subject(s) - medicine , pulse pressure , pulse wave velocity , blood pressure , arterial stiffness , cardiology , framingham heart study , heart rate , framingham risk score , disease
Brachial pulse pressure (PP) is physiologically higher than central PP. This PP amplification, which protects the heart from increased afterload, is related to the progressive increase of arterial stiffness along the vascular tree and subsequent changes in pressure wave reflections. The PP amplification increases with high heart rate (HR), which is observed in subjects with metabolic syndrome (MS). The objective of this study was to investigate whether PP amplification is affected by MS and is related to cardiovascular (CV) risk.
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