Nitric Oxide Release Is Impaired in Hypertensive Individuals With Familial History of Stroke | Zendy

Francesco Cosentino | Zendy; Pietro Francia | Zendy; Beatrice Musumeci | Zendy; L DESIATI | Zendy; M RAO | Zendy; Nicola De Luca | Zendy; Cristina Balla | Zendy; F DESENSI | Zendy; Massimo Volpe | Zendy

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Nitric Oxide Release Is Impaired in Hypertensive Individuals With Familial History of Stroke

Author(s) -

Francesco Cosentino,

Pietro Francia,

Beatrice Musumeci,

L DESIATI,

M RAO,

Nicola De Luca,

Cristina Balla,

F DESENSI,

Massimo Volpe

Publication year - 2006

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2006.06.002

Subject(s) - medicine , stroke (engine) , vasodilation , population , family history , hyperaemia , basal (medicine) , cardiology , reactive hyperemia , blood flow , endocrinology , mechanical engineering , environmental health , insulin , engineering

A genetic origin of cerebrovascular accidents has long been suspected on the basis of epidemiologic evidence and familial aggregation. Nevertheless, the final phenotype is largely influenced by concomitant risk factors. We aimed to investigate whether impairment of endothelium-dependent vasodilation can be used as an informative intermediate vascular phenotype in hypertensive patients with familial history of stroke.

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