High Systolic Blood Pressure Is Associated With Val/Val Genotype in the Catechol-O-Methyltransferase GeneThe Nord-Trøndelag Health Study (HUNT) | Zendy

Knut Hagen | Zendy; Erik O. Pettersen | Zendy; Lars Jacob Stovner | Zendy; Frank Skorpen | Zendy; Jostein Holmen | Zendy; JohnAnker Zwart | Zendy

Open Access

High Systolic Blood Pressure Is Associated With Val/Val Genotype in the Catechol-O-Methyltransferase GeneThe Nord-Trøndelag Health Study (HUNT)

Author(s) -

Knut Hagen,

Erik O. Pettersen,

Lars Jacob Stovner,

Frank Skorpen,

Jostein Holmen,

JohnAnker Zwart

Publication year - 2006

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2006.05.023

Subject(s) - genotype , medicine , blood pressure , catechol o methyl transferase , odds ratio , polymorphism (computer science) , diastole , endocrinology , population , genetics , gene , biology , environmental health

The catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met. A few studies on animals have shown a relationship between the COMT gene and BP, but whether this exists in human beings is unclear. The aim of this study was to evaluate the relationship between codon 158 COMT gene polymorphism and BP in a population-based cohort.

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