Open AccessVascular-Specific Increase in Exon 1b-Encoded CaV1.2 Channels in Spontaneously Hypertensive Rats
Author(s) -
W WANG,
Nehad Saada,
B. Dai,
Li Pang,
Philip Palade
Publication year - 2006
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2006.01.020
Subject(s) - gene isoform , exon , downregulation and upregulation , medicine , endocrinology , blot , vascular smooth muscle , translation (biology) , messenger rna , microbiology and biotechnology , gene , biology , smooth muscle , biochemistry
The vasculature of the adult spontaneously hypertensive rat (SHR) is known to express more functional L-type Ca channels than the vasculature of normotensive Wistar Kyoto (WKY) rats, but it is not known which Ca(V)1.2 channel isoform is upregulated.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom