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In many genetic studies of complex traits, sample sizes are often too small to detect linkages of low-to-moderate effects. However, the combined linkage evidence across several studies can be synthesized using meta-analysis with the aim of providing more definitive support of linkage.

american journal of hypertension

Meta-Analysis of Genome-Wide Scans for Blood Pressure in African American and Nigerian SamplesThe National Heart, Lung, and Blood Institute GeneLink Project