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Meta-Analysis of Genome-Wide Scans for Blood Pressure in African American and Nigerian SamplesThe National Heart, Lung, and Blood Institute GeneLink Project
Author(s) -
Treva Rice,
Stephen S. Rich,
Xiaofeng Wu,
Claude Bouchard,
Tuomo Rankinen,
D RAO,
Cashell E. Jaquish,
R. R. Fabsitz,
Mike Province
Publication year - 2006
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2005.09.006
Subject(s) - medicine , linkage (software) , blood pressure , sample size determination , meta analysis , genome , genetic linkage , genome wide association study , genetics , statistics , genotype , biology , gene , mathematics , single nucleotide polymorphism
In many genetic studies of complex traits, sample sizes are often too small to detect linkages of low-to-moderate effects. However, the combined linkage evidence across several studies can be synthesized using meta-analysis with the aim of providing more definitive support of linkage.

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