Plasma Osteopontin Levels Are Higher in Patients With Primary Aldosteronism Than in Patients With Essential Hypertension | Zendy

Jun Irita | Zendy; T Okura | Zendy; Seiko Manabe | Zendy; Mie Kurata | Zendy; K MIYOSHI | Zendy; Shinichi Watanabe | Zendy; Takuya Fukuoka | Zendy; Jitsuo Higaki | Zendy

Open Access

Plasma Osteopontin Levels Are Higher in Patients With Primary Aldosteronism Than in Patients With Essential Hypertension

Author(s) -

Jun Irita,

T Okura,

Seiko Manabe,

Mie Kurata,

K MIYOSHI,

Shinichi Watanabe,

Takuya Fukuoka,

Jitsuo Higaki

Publication year - 2006

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2005.08.019

Subject(s) - medicine , primary aldosteronism , essential hypertension , osteopontin , aldosterone , blood pressure , endocrinology , inflammation , tumor necrosis factor alpha , secondary hypertension , c reactive protein

The incidence of cardiovascular events is higher in patients with primary aldosteronism (PA) than in patients with essential hypertension (EHT). Aldosterone has been shown to play an important role in the development of vascular inflammation and myocardial fibrosis in animal models. Elevated serum inflammatory cytokine is an independent cardiovascular risk factor in patients with EHT. In the present study, we compared levels of inflammatory cytokines between patients with PA and EHT.

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