Relationship Between Circulating Plasma Matrix Metalloproteinase-9 (gelatinase-B) Concentration and Aortic Root Dilatation
Author(s) -
O Karakaya,
İrfan Barutçu,
Ali Metin Esen,
Serkan Doğan,
Mutlu Sağlam,
Hekim Karapınar,
Taylan Akgün,
Yusuf Karavelioğlu,
Özlem Esen,
Nihal Özdemir
Publication year - 2006
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2005.08.013
Subject(s) - medicine , cardiology , matrix metalloproteinase , aortic root , matrix metalloproteinase 9 , gelatinase , gelatinase a , aorta
Expression of matrix metalloproteinase (MMP) has been shown in aortic dissection and aneurysms indicating increased proteolysis compared with the normal aorta. However, its role in the development of aortic root dilatation has not been studied. We therefore attempted to determine the relationship between aortic root diameter and MMP-9 concentration in a hypertensive population.
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