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Combination of Exercise and Enalapril Enhances Renoprotective and Peripheral Effects in Rats With Renal Ablation
Author(s) -
Motoyori Kanazawa,
Takeshi Kawamura,
L LI,
Y. Sasaki,
Kenji Matsumoto,
Hitomi Kataoka,
Osamu Ito,
Naoki Minami,
Tokutaro Sato,
Tetsuya Ootaka
Publication year - 2006
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2005.07.009
Subject(s) - medicine , renal function , endocrinology , enalapril , blood urea nitrogen , creatinine , glomerulosclerosis , proteinuria , renal blood flow , renal cortex , urology , blood pressure , kidney , angiotensin converting enzyme
It is suggested that appropriate chronic exercise (EX) may produce improvements of the physical strength in patients with chronic renal failure (CRF). Because acute exercise causes proteinuria and decreases the renal blood flow and glomerular filtration rate, it is necessary to consider the influence of EX on renal function. Therefore, we assessed the renal and peripheral effects of moderate to intense EX as well as the effects of the combination of EX and enalapril (ENA) in a rat model of CRF.

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