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Does Aldosterone-to-Renin Ratio Predict the Antihypertensive Effect of the Aldosterone Antagonist Spironolactone?
Author(s) -
A MAHMUD,
Mohamed Mahgoub,
Megan Hall,
J. Feely
Publication year - 2005
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2005.06.010
Subject(s) - spironolactone , medicine , aldosterone , blood pressure , endocrinology , plasma renin activity , essential hypertension , diastole , population , renin–angiotensin system , environmental health
The recognition that some 10% to 15% of the hypertensive population may have aldosterone excess has increased the frequency of measurement of the aldosterone-to-renin ratio (ARR) and the use of aldosterone antagonists. Whether this ratio will predict the blood pressure (BP) response to spironolactone is not clear.

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