Effect of BQ-123, an Endothelin Antagonist, on Renal Hemodynamics, Tubular Function, Vasoactive Hormones, and Blood Pressure in Healthy Humans: A Dose Response Study | Zendy

E PEDERSEN | Zendy; Ingrid K. Thomsen | Zendy; L FJORDSIDE | Zendy

Open Access

Effect of BQ-123, an Endothelin Antagonist, on Renal Hemodynamics, Tubular Function, Vasoactive Hormones, and Blood Pressure in Healthy Humans: A Dose Response Study

Author(s) -

E PEDERSEN,

Ingrid K. Thomsen,

L FJORDSIDE

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2005.06.008

Subject(s) - medicine , vasoactive , blood pressure , hemodynamics , antagonist , endothelin receptor , hormone , endocrinology , renal function , renal blood flow , effective renal plasma flow , receptor

Endothelin contributes to the maintenance of vascular tonus in both the systemic circulation and in regional vascular beds. The purpose of the study was to measure the effect of the endothelin A antagonist BQ-123 on renal hemodynamics, tubular function, vasoactive hormones, and blood pressure (BP) in healthy men.

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