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A successful weight loss program is essential treatment for obesity-related diseases, but it is well known that the majority of individuals do not succeed in weight loss maintenance. The present study evaluates hormonal mechanisms and the relationship of beta2-adrenoceptor polymorphisms involved in individuals who regain weight after initially successful weight loss.

Rebound Weight Gain as Associated With High Plasma Norepinephrine Levels That Are Mediated Through Polymorphisms in the β2-Adrenoceptor