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Felodipine–Metoprolol Combination Tablet: Maintained Health-Related Quality of Life in the Presence of Substantial Blood Pressure Reduction
Author(s) -
Björn Dahlöf,
Alessio Degl’Innocenti,
D ELMFELDT,
J PUIG,
Thomas E. Gundersen,
J Hosie,
W Januszewicź,
C LINDSTROM,
D Magometschnigg,
Paul H. Tanser
Publication year - 2005
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2005.04.017
Subject(s) - medicine , felodipine , metoprolol , blood pressure , placebo , enalapril , diastole , quality of life (healthcare) , randomized controlled trial , hydrochlorothiazide , anesthesia , angiotensin converting enzyme , alternative medicine , nursing , pathology
Most treated hypertensive patients do not achieve adequate blood pressure (BP) control. Initiating therapy with two drugs has been suggested when BP is >20/10 mm Hg above goal. To ensure patients' compliance, such treatment needs to be well tolerated and must not compromise health-related quality of life (HRQL). The primary objective of this study was to compare the effects on HRQL of initiating treatment with felodipine + metoprolol (F+M) fixed combination tablets, or enalapril (E), or placebo (P).

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