Insulin-Stimulated NAD(P)H Oxidase Activity Increases Migration of Cultured Vascular Smooth Muscle Cells | Zendy

Mu Yang | Zendy; E. Foster | Zendy; A Kahn | Zendy

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Insulin-Stimulated NAD(P)H Oxidase Activity Increases Migration of Cultured Vascular Smooth Muscle Cells

Author(s) -

Mu Yang,

E. Foster,

A Kahn

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2005.04.012

Subject(s) - nad(p)h oxidase , nad+ kinase , medicine , endocrinology , insulin , vascular smooth muscle , angiotensin ii , superoxide , nitric oxide , oxidase test , nadph oxidase , enzyme , biology , biochemistry , oxidative stress , receptor , smooth muscle

We reported that insulin stimulates NAD(P)H oxidase activity but not migration of cultured rat vascular smooth muscle cells (VSMCs). Because angiotensin II (Ang II) increases NAD(P)H oxidase activity in these cells, we wished to determine whether insulin stimulates migration of Ang II-treated VSMCs by synergistically stimulating enzyme activity.

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