Effect of Exogenous Urotensin-II on Vascular Tone in Skin Microcirculation of Patients With Essential Hypertension | Zendy

Brigitte M. Sondermeijer | Zendy; Andrew R. Kompa | Zendy; Paul A. Komesaroff | Zendy; Henry Krum | Zendy

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Effect of Exogenous Urotensin-II on Vascular Tone in Skin Microcirculation of Patients With Essential Hypertension

Author(s) -

Brigitte M. Sondermeijer,

Andrew R. Kompa,

Paul A. Komesaroff,

Henry Krum

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2005.03.748

Subject(s) - medicine , urotensin ii , microcirculation , vasodilation , iontophoresis , laser doppler velocimetry , essential hypertension , endocrinology , vasoconstriction , cardiology , blood flow , blood pressure , receptor , radiology

Plasma levels of urotensin-II (U-II) have been found to be elevated in patients with essential hypertension. However, the consequence of activation of the U-II system have not been previously determined in these patients. We therefore compared the effect of exogenous U-II administration on vascular tone in hypertensive patients (n = 13) and normotensive subjects (n = 14).

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