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To stablish early values of left ventricular diastolic pressure (LVEDP) in spontaneously hypertensive rats (SHR), we studied 40 SRH which were submitted to a cardiac catheterization to evalue the following parameters: systolic and diastolic pressure, LVEDP and Dp/Dt values.All SHR were males and they were 12 weeks of age. They were keep in our animal lab at 26 to 32 °C. Results were compared with others 40 normotensive rats of similar age.We show results in the following table:

Early elevation of left ventricular end diastolic pressure in spontaneously hypertensive rats comparing with normotensive rats. Experimental study