Diabetes mellitus is very common in drug resistant hypertension against angiotensin II receptor blocker and ACE inhibitor | Zendy

Katsumi Eguchi | Zendy; Kazuomi Kario | Zendy; Jun Ishikawa | Zendy; Satoshi Hoshide | Zendy; Masato Morinari | Zendy; Kenei Shimada | Zendy

Open Access

Diabetes mellitus is very common in drug resistant hypertension against angiotensin II receptor blocker and ACE inhibitor

Author(s) -

Katsumi Eguchi,

Kazuomi Kario,

Jun Ishikawa,

Satoshi Hoshide,

Masato Morinari,

Kenei Shimada

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2005.03.155

Subject(s) - medicine , candesartan , lisinopril , ace inhibitor , diabetes mellitus , angiotensin receptor , diuretic , antihypertensive drug , angiotensin converting enzyme , pharmacology , telmisartan , urology , endocrinology , blood pressure , angiotensin ii

The rise of the V’O2AT and the WRAT was slightly but non significantly higher in the ACE inhibitors group than in the control. Among hypertensive patients with DD/DI genotype (high ACE activity), ACE inhibition was not associated with a better improvement in exercise endurance after training. Thus, despite the apparent advantage of the II ACE polymorphism (low ACE activity) on fitness, ACE activity is not the direct modulator of the effect of training.

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