Pioglitazone Improves Left Ventricular Diastolic Function in Patients With Essential Hypertension
Author(s) -
T. Horio,
Masayasu Suzuki,
Keita Suzuki,
Itaru Takamisawa,
Aki Hiuge,
Kei Kamide,
Shin Takiuchi,
Yoshio Iwashima,
Shinji Kihara,
T. Funahashi
Publication year - 2005
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2005.02.003
Subject(s) - medicine , pioglitazone , diastole , insulin resistance , cardiology , adiponectin , endocrinology , left ventricular hypertrophy , insulin , blood pressure , body mass index , diabetes mellitus , type 2 diabetes
Left ventricular (LV) hypertrophy and diastolic dysfunction, which are common cardiac consequences of hypertension, are modified by insulin resistance. The present study assessed the hypothesis that primary treatment of insulin resistance may reverse such cardiac changes in hypertensive patients.
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