Antioxidant Enzymes and Effects of Tempol on the Development of Hypertension Induced by Nitric Oxide Inhibition | Zendy

Juan Sáinz | Zendy; Rosemary Wangensteen | Zendy; Isabel RodríguezGómez | Zendy; Juan Manuel Moreno | Zendy; Virginia Chamorro | Zendy; A. España Osuna | Zendy; P. Bueno | Zendy; F Vargas | Zendy

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Antioxidant Enzymes and Effects of Tempol on the Development of Hypertension Induced by Nitric Oxide Inhibition

Author(s) -

Juan Sáinz,

Rosemary Wangensteen,

Isabel RodríguezGómez,

Juan Manuel Moreno,

Virginia Chamorro,

A. España Osuna,

P. Bueno,

F Vargas

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2004.12.022

Subject(s) - glutathione peroxidase , medicine , superoxide dismutase , antioxidant , nitric oxide , glutathione reductase , catalase , pharmacology , glutathione , essential hypertension , enzyme , endocrinology , oxidative stress , biochemistry , blood pressure , chemistry

This study analyzed whether hypertension induced by N(omega)-nitro-l-arginine methyl ester (L-NAME) is associated with dysregulation of the main antioxidant enzymes (superoxide dismutase [SOD], catalase, glutathione peroxidase [GPX], and glutathione reductase [GR]) and whether chronic administration of tempol ameliorates this hypertension.

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