Chronic administration of resveratrol prevents biochemical cardiovascular changes in fructose-fed rats | Zendy

Roberto Miatello | Zendy; Mary Carmen Vázquez | Zendy; Nicolás Federico Renna | Zendy; Montserrat Cruzado | Zendy; Amira Ponce Zumino | Zendy; Norma Risler | Zendy

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Chronic administration of resveratrol prevents biochemical cardiovascular changes in fructose-fed rats

Author(s) -

Roberto Miatello,

Mary Carmen Vázquez,

Nicolás Federico Renna,

Montserrat Cruzado,

Amira Ponce Zumino,

Norma Risler

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2004.12.012

Subject(s) - tbars , medicine , endocrinology , enos , endothelial dysfunction , lipid peroxidation , insulin resistance , resveratrol , thiobarbituric acid , blood pressure , fructose , nitric oxide , oxidative stress , nitric oxide synthase , insulin , pharmacology , biochemistry , biology

There seems to be a link between the cluster of risk factors known as insulin resistance syndrome with endothelial dysfunction. Resveratrol (3,4,5-trihydroxyestilbene) (RV), an antioxidant found in many components of the human diet, has been proposed as an effective agent in the prevention of several pathologic processes. This study examined the effect of chronic administration of RV on endothelial nitric oxide synthase (eNOS) activity in cardiovascular tissues and on plasma lipid peroxidation in fructose-fed rats (FFR), an experimental model of this syndrome.

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