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Postural change in systolic blood pressure (SBP) is prospectively associated with several disease outcomes including hypertension, stroke, and coronary heart disease. The objective of this study was to characterize further a possible quantitative trait locus on chromosome 18q21 influencing SBP response to a postural challenge.

american journal of hypertension

Further Evidence of a Quantitative Trait Locus on Chromosome 18 Influencing Postural Change in Systolic Blood Pressure: The Hypertension Genetic Epidemiology Network (HyperGEN) Study