Genome-Wide Linkage Study of Erythrocyte Sodium-Lithium Countertransport | Zendy

Alanna C. Morrison | Zendy; E BOERWINKLE | Zendy; Stephen T. Turner | Zendy; R. E. Ferrell | Zendy

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Genome-Wide Linkage Study of Erythrocyte Sodium-Lithium Countertransport

Author(s) -

Alanna C. Morrison,

E BOERWINKLE,

Stephen T. Turner,

R. E. Ferrell

Publication year - 2005

Publication title -

american journal of hypertension

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2004.11.030

Subject(s) - medicine , lithium (medication) , linkage (software) , sodium , genome , genetics , gene , biology , chemistry , organic chemistry

Increased erythrocyte sodium-lithium countertransport (SLC) has been observed in patients with essential hypertension. An analytic strategy for identification of genetic variation contributing to hypertension is the evaluation of appropriate intermediate phenotypes for hypertension, such as SLC. Thus, in this study, genome-wide linkage scans for SLC were performed in two independent samples of pedigrees from the Rochester Family Heart Study (RFHS).

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