Open AccessPossible involvement of aminopeptidase A in hypertension and renal damage in Dahl salt-sensitive rats
Author(s) -
Michio Nomura,
Sachiko Nomura,
Takashi Mitsui,
Masaki Suzuki,
Hiroshi Kobayashi,
Toshiyuki Ito,
A. Itakura,
Fumitaka Kikkawa,
S MIZUTANI
Publication year - 2005
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2004.11.010
Subject(s) - medicine , endocrinology , blood pressure , aminopeptidase , biochemistry , amino acid , leucine , chemistry
Although aminopeptidase A (APA), which is abundant in the kidneys, is responsible for metabolizing angiotensin II (Ang II), its association with salt sensitivity remains uncertain. We aimed to clarify the involvement of APA in salt-induced hypertension and renal damage.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom