Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients | Zendy

Adviye Ergul | Zendy; Vera PortikDobos | Zendy; Josephine Hutchinson | Zendy; Jeferson Luís Franco | Zendy; Mark P. Anstadt | Zendy

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Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients

Author(s) -

Adviye Ergul,

Vera PortikDobos,

Josephine Hutchinson,

Jeferson Luís Franco,

Mark P. Anstadt

Publication year - 2004

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2004.06.025

Subject(s) - matrix metalloproteinase , medicine , downregulation and upregulation , extracellular matrix , metalloproteinase , matrix metalloproteinase 9 , inducer , vascular smooth muscle , activator (genetics) , tissue inhibitor of metalloproteinase , vascular disease , microbiology and biotechnology , endocrinology , biochemistry , receptor , biology , smooth muscle , gene

Peripheral vasculature undergoes extensive vascular remodeling in the hypertensive state. Regulation of extracellular matrix turnover by the matrix metalloproteinase (MMP) system is an important step in the vascular remodeling process. However, the expression pattern of the vascular MMP system in human hypertension remained unknown.

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