Insulin receptor number is reduced in healthy offspring of patients with essential hypertension | Zendy

T. Makris | Zendy; Ioannis Paizis | Zendy; P. Krespi | Zendy; Georgios Stavroulakis | Zendy; Ourania Papazachou | Zendy; D.P. Papadopoulos | Zendy; A. Hatzizacharias | Zendy; V. Votteas | Zendy

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Insulin receptor number is reduced in healthy offspring of patients with essential hypertension

Author(s) -

T. Makris,

Ioannis Paizis,

P. Krespi,

Georgios Stavroulakis,

Ourania Papazachou,

D.P. Papadopoulos,

A. Hatzizacharias,

V. Votteas

Publication year - 2004

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2004.05.012

Subject(s) - offspring , hyperinsulinemia , medicine , endocrinology , blood pressure , essential hypertension , insulin resistance , insulin , insulin receptor , metabolic syndrome , body mass index , receptor , diastole , diabetes mellitus , biology , pregnancy , genetics

Epidemiologic studies have shown that healthy offspring of hypertensive patients exhibit many features of the metabolic syndrome, such as hyperinsulinemia, insulin resistance, and lipid disorders. Patients with essential hypertension have reduced numbers of insulin receptors. The aim of this study was to examine whether the number of insulin receptors is reduced in the erythrocytes of healthy offspring of hypertensive patients in comparison to the offspring of healthy normotensive subjects.

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