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Pravastatin has an additional depressor effect in patients undergoing long-term treatment with antihypertensive drugs
Author(s) -
Toshio Ikeda,
Jun Sakùrai,
Daisuke Nakayama,
Yoshihiro Takahashi,
Kiyoko Matsuo,
Yuko Shibuya,
Tomoko Gomi,
Hidekazu Moriya,
Shuzo Kobayashi
Publication year - 2004
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2004.02.002
Subject(s) - pravastatin , medicine , probucol , rosuvastatin , crossover study , antihypertensive drug , doxazosin , cardiology , blood pressure , pharmacology , cholesterol , alternative medicine , pathology , placebo
Statins have been reported to have direct vascular effects independent of cholesterol reduction. To assess the antihypertensive effect of statins, a crossover study was designed to compare the depressor effect of pravastatin and probucol in hypertensive patients undergoing long-term treatment with antihypertensive drugs.

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