Blood pressure and cardiac autonomic nervous system in obese type 2 diabetic patients: effect of metformin administration | Zendy

Daniela Manzella | Zendy

Open Access

Blood pressure and cardiac autonomic nervous system in obese type 2 diabetic patients: effect of metformin administration

Author(s) -

Daniela Manzella

Publication year - 2004

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2003.11.006

Subject(s) - medicine , metformin , endocrinology , insulin resistance , blood pressure , hyperinsulinemia , type 2 diabetes , insulin , heart rate , diabetes mellitus , autonomic nervous system

Hyperinsulinemia/insulin resistance and elevated plasma free fatty acids (FFA) levels are involved in the hypertension and cardiac sympathetic overactivity. Metformin improves insulin action and lower plasma FFA concentrations. We investigate the possible effect of metformin on arterial blood pressure (BP) and cardiac sympathetic nervous system.

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