Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats
Author(s) -
Ming-Sheng Zhou
Publication year - 2004
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2003.09.007
Subject(s) - amlodipine , medicine , oxidative stress , angiotensin ii , endocrinology , endothelial dysfunction , calcium channel , angiotensin receptor , pharmacology , endothelium , receptor , calcium , blood pressure
Calcium channel blockers such as amlodipine are effective antihypertensive agents. In this study we investigated the effects of amlodipine on vascular oxidative stress, expression of the lectin-like oxidized low-density lipoprotein receptor (LOX-1), and endothelial function in angiotensin (Ang) II-infused rats.
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