Antihypertensive effects of two fixed-dose combinations of losartan and hydrochlorothiazide versus hydrochlorothiazide monotherapy in subjects with ambulatory systolic hypertension | Zendy

Yves Lacourcière | Zendy; Luc Poirier | Zendy

Open Access

Antihypertensive effects of two fixed-dose combinations of losartan and hydrochlorothiazide versus hydrochlorothiazide monotherapy in subjects with ambulatory systolic hypertension

Author(s) -

Yves Lacourcière,

Luc Poirier

Publication year - 2003

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2003.07.014

Subject(s) - hydrochlorothiazide , medicine , losartan , diuretic , isolated systolic hypertension , ambulatory , fixed dose combination , cardiology , thiazide , blood pressure , ambulatory blood pressure , diastole , systole , urology , pharmacology , angiotensin ii

The efficacy of losartan (L) in combination with hydrochlorothiazide (HCTZ) has been demonstrated to reduce blood pressure. However, there are limited data on the effects of L/HCTZ combinations versus HCTZ monotherapies in reducing ambulatory systolic blood pressure. The aim of this study was to compare the effects of these treatment approaches in patients with ambulatory systolic hypertension.

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