Association between impaired IL-10 production following exposure to Staphylococcus aureus enterotoxin B and disease severity in eosinophilic chronic rhinosinusitis | Zendy

Takenori Haruna | Zendy; Shin Kariya | Zendy; Tazuko Fujiwara | Zendy; Takaya Higaki | Zendy; Seiichiro Makihara | Zendy; Kengo Kanai | Zendy; Rumi Fujiwara | Zendy; Satoshi Iwasaki | Zendy; Yoshihiro Noguchi | Zendy; Kazunori Nishizaki | Zendy; Mitsuhiro Okano | Zendy

Open Access

Association between impaired IL-10 production following exposure to Staphylococcus aureus enterotoxin B and disease severity in eosinophilic chronic rhinosinusitis

Author(s) -

Takenori Haruna,

Shin Kariya,

Tazuko Fujiwara,

Takaya Higaki,

Seiichiro Makihara,

Kengo Kanai,

Rumi Fujiwara,

Satoshi Iwasaki,

Yoshihiro Noguchi,

Kazunori Nishizaki,

Mitsuhiro Okano

Publication year - 2018

Publication title -

allergology international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.49

H-Index - 58

eISSN - 1440-1592

pISSN - 1323-8930

DOI - 10.1016/j.alit.2018.02.001

Subject(s) - enterotoxin , chronic rhinosinusitis , staphylococcus aureus , medicine , eosinophilic , immunology , disease , pathology , biology , gene , bacteria , genetics , escherichia coli

IL-10 is a major anti-inflammatory cytokine that prevents inflammation-mediated tissue damage. We characterized the production of IL-10 by sinonasal tissue cells following exposure to Staphylococcus aureus enterotoxin B (SEB), which elicits cellular responses and is associated with the pathogenesis of eosinophilic chronic rhinosinusitis (ECRS).

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