Serum levels of squamous cell carcinoma antigens 1 and 2 reflect disease severity and clinical type of atopic dermatitis in adult patients | Zendy

Tomoko Okawa | Zendy; Yukie Yamaguchi | Zendy; Kenzen Kou | Zendy; Junya Ono | Zendy; Yoshinori Azuma | Zendy; Noriko Komitsu | Zendy; Yusuke Inoue | Zendy; Masumi Kohno | Zendy; Setsuko Matsukura | Zendy; Takeshi Kambara | Zendy; Shoichiro Ohta | Zendy; Kenji Izuhara | Zendy; Michiko Aihara | Zendy

Open Access

Serum levels of squamous cell carcinoma antigens 1 and 2 reflect disease severity and clinical type of atopic dermatitis in adult patients

Author(s) -

Tomoko Okawa,

Yukie Yamaguchi,

Kenzen Kou,

Junya Ono,

Yoshinori Azuma,

Noriko Komitsu,

Yusuke Inoue,

Masumi Kohno,

Setsuko Matsukura,

Takeshi Kambara,

Shoichiro Ohta,

Kenji Izuhara,

Michiko Aihara

Publication year - 2017

Publication title -

allergology international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.49

H-Index - 58

eISSN - 1440-1592

pISSN - 1323-8930

DOI - 10.1016/j.alit.2017.06.016

Subject(s) - atopic dermatitis , immunology , biomarker , immunoglobulin e , medicine , eosinophil , antigen , biology , antibody , asthma , biochemistry

Recent studies have indicated that serum levels of squamous cell carcinoma antigen (SCCA) 1 and 2 induced by type 2 cytokines such as IL-4 and IL-13, are increased in patients with atopic dermatitis (AD). However, no clinical studies have analyzed serum levels of SCCA2 in larger series of AD patients or their association with various clinical characteristics. This study was performed to clarify whether serum levels of SCCA2 are associated with disease severity and clinical phenotypes of adult AD patients.

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