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Circulating activated innate lymphoid cells and mucosal-associated invariant T cells are associated with airflow limitation in patients with asthma
Author(s) -
Ayako Ishimori,
Norihiro Harada,
Asako Chiba,
Sonoko Harada,
Kei Matsuno,
Fumihiko Makino,
Jun Ito,
Shoichiro Ohta,
Junya Ono,
Ryo Atsuta,
Kenji Izuhara,
Kazuhisa Takahashi,
Sachiko Miyake
Publication year - 2016
Publication title -
allergology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.49
H-Index - 58
eISSN - 1440-1592
pISSN - 1323-8930
DOI - 10.1016/j.alit.2016.07.005
Subject(s) - innate lymphoid cell , asthma , immunology , medicine , innate immune system , immune system
A variety of innate subsets of lymphoid cells such as natural killer (NK) cells, several populations of innate lymphoid cells (ILCs), and mucosal-associated invariant T (MAIT) cells as innate-like T lymphocytes are involved in asthma and may have important effector functions in asthmatic immune responses. In the present study, we investigated whether NK cells, ILCs, and MAIT cells in the peripheral blood of patients with asthma would be associated with clinical asthma parameters.

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