Imbalance of endogenous prostanoids in moderate-to-severe asthma
Author(s) -
Masaya Takemura,
Akio Niimi,
Hisako Matsumoto,
Tetsuya Ueda,
Masafumi Yamaguchi,
Hirofumi Matsuoka,
Makiko Jinnai,
Kian Fan Chung,
Michiaki Mishima
Publication year - 2016
Publication title -
allergology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.49
H-Index - 58
eISSN - 1440-1592
pISSN - 1323-8930
DOI - 10.1016/j.alit.2016.05.013
Subject(s) - prostanoid , prostaglandin e2 , medicine , prostaglandin , sputum , asthma , thromboxane b2 , thromboxane , endocrinology , thromboxane a2 , prostaglandin d2 , clinical significance , immunology , pathology , receptor , platelet , tuberculosis
Inhalation studies suggested "protective" roles of exogenous prostaglandin E 2 , but the clinical relevance of endogenous prostanoids in asthma is poorly known. The objective of this study is to measure sputum levels of prostanoids in asthmatic patients to correlate with clinical indices.
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