Effects of sublingual immunotherapy in a murine asthma model sensitized by intranasal administration of house dust mite extracts
Author(s) -
Kenjiro Shima,
Toshiyuki Koya,
Keisuke Tsukioka,
Takuro Sakagami,
Takashi Hasegawa,
Chiharu Fukano,
Katsuyo OhashiDoi,
Satoshi Watanabe,
Eiichi Suzuki,
Toshiaki Kikuchi
Publication year - 2016
Publication title -
allergology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.49
H-Index - 58
eISSN - 1440-1592
pISSN - 1323-8930
DOI - 10.1016/j.alit.2016.05.012
Subject(s) - slit , medicine , nasal administration , immunology , bronchoalveolar lavage , house dust mite , eosinophilia , pulmonary eosinophilia , immunotherapy , allergen , asthma , allergy , lung , immune system , eosinophil , biology , genetics
Sublingual immunotherapy (SLIT) has received attention as a method for allergen immunotherapy. However, the mechanism of SLIT has not yet been fully investigated. Therefore, we evaluated the effects of SLIT in a murine asthma model, sensitized by intranasal administration of house dust mite (HDM) extracts.
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