Intravital imaging technology reveals immune system dynamics in vivo
Author(s) -
Masaru Ishii
Publication year - 2016
Publication title -
allergology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.49
H-Index - 58
eISSN - 1440-1592
pISSN - 1323-8930
DOI - 10.1016/j.alit.2016.05.001
Subject(s) - intravital microscopy , live cell imaging , living systems , optical imaging , multiphoton fluorescence microscope , preclinical imaging , nanotechnology , fluorescence lifetime imaging microscopy , immune system , fluorescence , biology , in vivo , fluorescence microscope , computer science , cell , materials science , physics , immunology , artificial intelligence , optics , genetics , microbiology and biotechnology
Fluorescent 'intravital' imaging is a new research technique by which the interior of living tissues and organs (in living bodies, if possible) can be observed, revealing the kinetics of cell and molecular processes in real time. Recent technological innovations in optical equipment and fluorescence imaging techniques have enabled a variety of cellular phenomena in different tissues and organs to be characterized under completely native conditions. This shift from static to dynamic biology constitutes the beginning of a new era in biomedical sciences.
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