Measuring local immunoglobulin E in the inferior turbinate nasal mucosa in patients with allergic rhinitis
Author(s) -
Yasushi Ota,
Yoshihiro Ikemiyagi,
Toshiya Sato,
Tatsuo Funakoshi,
Nobuyuki Hiruta,
Makoto Kitamura,
Hideaki Bujo,
Mitsuya Suzuki
Publication year - 2016
Publication title -
allergology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.49
H-Index - 58
eISSN - 1440-1592
pISSN - 1323-8930
DOI - 10.1016/j.alit.2016.03.009
Subject(s) - immunoglobulin e , mucous membrane of nose , medicine , immunology , nose , allergen , antibody , allergy , pathology , surgery
Studies show that immunoglobulin E (IgE) is produced in the local nasal mucosa in allergic rhinitis patients. However, no study involved the measurement of IgE levels in the local nasal mucosal tissue in allergic rhinitis patients. This study aimed to measure the local IgE levels in the nasal mucosal tissue and to compare the levels of total IgE and specific IgEs in the serum and the inferior turbinate nasal mucosa in allergic rhinitis patients using the AlaSTAT 3gAllergy assay (Siemens Healthcare Diagnostics AG, Erlangen, Germany).
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