Case for diagnosis. Cutaneous small vessel vasculitis (anti-proteinase 3 positive), fever, hemoptysis, and lung cavitation in an adult | Zendy

Luana Moraes Campos | Zendy; Mariana Righetto de Ré Lai | Zendy; Priscila Neri Lacerda | Zendy; Hélio Amante Miot | Zendy

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Case for diagnosis. Cutaneous small vessel vasculitis (anti-proteinase 3 positive), fever, hemoptysis, and lung cavitation in an adult

Author(s) -

Luana Moraes Campos,

Mariana Righetto de Ré Lai,

Priscila Neri Lacerda,

Hélio Amante Miot

Publication year - 2021

Publication title -

anais brasileiros de dermatologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.461

H-Index - 44

eISSN - 1806-4841

pISSN - 0365-0596

DOI - 10.1016/j.abd.2020.06.009

Subject(s) - medicine , vasculitis , bronchoalveolar lavage , purpura (gastropod) , pathology , histopathology , lung , tuberculosis , palpable purpura , henoch schonlein purpura , ecology , disease , biology

Small vessel vasculitis with anti-proteinase antibodies 3 is an atypical clinical presentation of tuberculosis. The authors present the case of a 47-year-old male patient, with palpable purpura and palmoplantar hemorrhagic blisters, with subsequent dissemination. He presented severe pulmonary symptoms with cavitation, fever, hemoptysis, and high levels of anti-proteinase 3. Histopathological assessment of the skin revealed small vessel vasculitis; pulmonary histopathology showed granulomas with caseation. Bronchoalveolar lavage was positive for alcohol-acid-fast bacilli. In countries with a high prevalence of tuberculosis, the presence of autoantibodies in a patient with vasculitis, fever, and pulmonary cavitation requires investigation of infectious causes.

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