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Case for diagnosis. Erythematous and infiltrated plaques in the infrahyoid region
Author(s) -
Natália Tenório Cavalcante Bezerra,
Antônio Pedro Mendes Schettini,
André Luiz Leturiondo,
Liana Hortencia Miranda Tubilla Mathias
Publication year - 2020
Publication title -
anais brasileiros de dermatologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 44
eISSN - 1806-4841
pISSN - 0365-0596
DOI - 10.1016/j.abd.2020.03.022
Subject(s) - histiocyte , leprosy , medicine , syphilis , rare disease , human immunodeficiency virus (hiv) , granulomatous disease , mycobacterium leprae , pathology , penicillin , dermatology , antiretroviral therapy , disease , antibiotics , immunology , biology , viral load , microbiology and biotechnology
Leprosy is a chronic infectious disease caused by Mycobacterium leprae and, depending on the host immune status, presents different clinical forms. This report describes the case of a 46-year-old man who had hypoesthetic lesions in the infrahyoid region for 30 days. The bacilloscopy was negative. The anatomopathological examination showed alterations corresponding to the tuberculoid pole (epithelioid histiocytes) and virchowian pole (foamy histiocytes), compatible with borderline-virchowian leprosy (Ridley and Jopling classification). Rapid tests for HIV I, II, and syphilis were positive, with a CD4 count of 223. The patient started treatment with multibacillary multidrug therapy, antiretroviral therapy, and benzathine penicillin, with marked clinical improvement in two months.

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