Multisystemic fusariosis with fulminant evolution | Zendy

Nelson Turra | Zendy; Agustina Acosta | Zendy; Andrea Incoronato | Zendy; Pilar Beltramo | Zendy

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Multisystemic fusariosis with fulminant evolution

Author(s) -

Nelson Turra,

Agustina Acosta,

Andrea Incoronato,

Pilar Beltramo

Publication year - 2020

Publication title -

anais brasileiros de dermatologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.461

H-Index - 44

eISSN - 1806-4841

pISSN - 0365-0596

DOI - 10.1016/j.abd.2020.03.007

Subject(s) - fulminant , fusariosis , medicine , skin biopsy , stereotactic biopsy , pathology , voriconazole , myeloid leukemia , biopsy , blisters , bone marrow , dermatology , surgery , antifungal , immunology , biology , fusarium , horticulture

This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters with hemorrhagic content inside. Skin biopsy evidenced intravascular filamentous structures. A blood culture confirmed the presence of Fusarium oxysporum. Intravenous treatment with voriconazole was initiated. The patient evolved unfavorably with multiple necrotic skin lesions, ischemic brain lesions, and death.

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