Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case–control study | Zendy

Yıldız Hayran | Zendy; Nuran Allı | Zendy; Pınar İncel Uysal | Zendy; Tuba Çandar | Zendy

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Association of CYP2J2 polymorphism with susceptibility to psoriasis in Turkish population: a case–control study

Author(s) -

Yıldız Hayran,

Nuran Allı,

Pınar İncel Uysal,

Tuba Çandar

Publication year - 2019

Publication title -

anais brasileiros de dermatologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.461

H-Index - 44

eISSN - 1806-4841

pISSN - 0365-0596

DOI - 10.1016/j.abd.2019.04.006

Subject(s) - psoriasis , turkish population , medicine , gastroenterology , genotype , case control study , allele , immunology , population , biology , genetics , gene , environmental health

Cytochrome P450 2J2 is mostly expressed in extrahepatic tissues; it metabolizes arachidonic acid to epoxyeicosatrienoic acids, with various cardio protective and anti-inflammatory effects. CYP2J2 polymorphism has been identified as a risk factor for cardiovascular diseases, but its association with psoriasis remains unknown.

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