Lack of association between mutation in IL36RN and palmoplantar pustular psoriasis in Chinese patients
Author(s) -
Xiaoling Yu,
Dan Shu,
Hongzhong Jin
Publication year - 2019
Publication title -
anais brasileiros de dermatologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.461
H-Index - 44
eISSN - 1806-4841
pISSN - 0365-0596
DOI - 10.1016/j.abd.2019.01.008
Subject(s) - palmoplantar pustulosis , pustulosis , generalized pustular psoriasis , medicine , dermatology , psoriasis , mutation , genetics , biology , immunology , gene , arthritis , synovitis
Palmoplantar pustulosis is considered to be a localized pustular psoriasis confined to the palms and soles. Mutation of the IL36RN gene, encoding interleukin-36 receptor antagonist (IL-36Ra), is associated with generalized pustular psoriasis, but IL36RN mutations in Chinese palmoplantar pustulosis patients have not previously been investigated.
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