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2003 mic therapy. Autonomic dysfunction was present in 70% of the hypertensive diabetic group and 40,4% the non-hypertensive group. In both groups were observed combined parasympathetic and sympathetic damage, but the frequency of abnonml LF/HF, was greater in hypertensive group (68% versus 31,9%, p<O,O5). A higher prevalence of increased of LF/HF was observed in patients with type 2 diabetes mellitus (59,5%). The patients with hypertension had a higher prevalence of ventricular extrasystoles Lawn grade III-V (VE) (44%) than those without hypertension (17%). VE correlated with the impaired sym-patovagal balance (r=O,68, p<O,O5). The prevalence of QT, prolongation was higher in hypertensive group than in non-hypertensive (55,1% versus 35,9%, p<O,O5). QT, interval was signiiicantly different between diabetic patients with and without hypertension (0,468&6,61ns " ~ versus 0,449&4,21ns " ~). QT, pro-longation correlated with VE and increased of LF/HF (r=O,42; r=0,86 p<O,O5). Hypertension had a negative influence on sympatovagal balance and length of QT, and is associated with high risk of ventricular tachyarrhythmias, especially is common with type 2 diabetic patients. Objectives: We assessed the longitudinal age-related changes in heart rate variability(HRV) and its circadian rhythm(CR) in the very elderly. Methods: In 15 healthy elderly subjects (mean age of 70.0&4.1, 64-80 yn.; at 1st recording, female 10) in whom Halter monitmings were conducted twice at an interval of 15 years, we assessed changes in HRV (meanNN, HF, LF, LF/HF) and its CR.

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