Open AccessSelective detection of the tolyl cation among other [C7H7]+ isomers by ion/molecule reaction with dimethyl ether
Author(s) -
Heath Tg,
John Allison,
Watson Jt
Publication year - 1991
Publication title -
journal of the american society for mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 127
eISSN - 1879-1123
pISSN - 1044-0305
DOI - 10.1016/1044-0305(91)80018-3
Subject(s) - chemistry , anisole , mass spectrometry , molecule , dimethyl ether , ion , polyatomic ion , fragmentation (computing) , triple quadrupole mass spectrometer , mass spectrum , ether , analytical chemistry (journal) , dissociation (chemistry) , collision induced dissociation , tandem mass spectrometry , selected reaction monitoring , organic chemistry , methanol , chromatography , computer science , operating system , catalysis
The ion/molecule reaction of the tolyl cation with dimethyl ether has been investigated using triple quadrupole mass spectrometry. Three isomers with [C7H7](+) composition, the 3-tolyl, benzyl, and tropylium cations, were individually selected and reacted with dimethyl ether at a pressure of 1 mtorr in the second quadrupole (Q2) collision cell. Only the tolyl ion reacted to yield a methoxylated product ion peak at m/z 122. This reaction product having m/z 122 is postulated to be identical in structure with the molecular ion of 3-methyl anisole, as supported by thermochemical data and the similarity of the collision induced dissociation (CID) daughter ion mass spectra of the product ion and the molecular ion of authentic 3-methyl anisole. The daughter ion mass spectra of the three [C7H7](+) isomers during CID, by using a triple quadrupole mass spectrometer, are nearly identical; on the other hand, the analytical approach based on the ion/molecule reaction with dimethyl ether clearly exhibits distinct gas-phase chemistry reflecting structural differences among the isomers. Sot.