Open AccessAssembly of Dynamic P450-Mediated Metabolons—Order Versus Chaos
Author(s) -
Jean-Étienne Bassard,
Birger Lindberg Møller,
Tomas Laursen
Publication year - 2017
Publication title -
current molecular biology reports
Language(s) - English
Resource type - Journals
ISSN - 2198-6428
DOI - 10.1007/s40610-017-0053-y
Subject(s) - computational biology , biochemical engineering , cytochrome p450 , synthetic biology , biology , metabolic pathway , computer science , metabolism , biochemistry , engineering
We provide an overview of the current knowledge on cytochrome P450-mediated metabolism organized as metabolons and factors that facilitate their stabilization. Essential parameters will be discussed including those that are commonly disregarded using the dhurrin metabolon from Sorghum bicolor as a case study.