Glioblastomas with oligodendroglial component-common origin of the different histological parts and genetic subclassification | Zendy

Barbara Klink | Zendy; Ben Schlingelhof | Zendy; Martin Klink | Zendy; Karen StoutWeider | Zendy; Stephan Patt | Zendy; Evelin Schröck | Zendy

Open Access

Glioblastomas with oligodendroglial component-common origin of the different histological parts and genetic subclassification

Author(s) -

Barbara Klink,

Ben Schlingelhof,

Martin Klink,

Karen StoutWeider,

Stephan Patt,

Evelin Schröck

Publication year - 2011

Publication title -

cellular oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.698

H-Index - 40

eISSN - 2211-3436

pISSN - 2211-3428

DOI - 10.1007/s13402-011-0034-8

Subject(s) - oligodendroglial tumor , oligodendroglioma , comparative genomic hybridization , pathology , biology , glioblastoma , in situ hybridization , fluorescence in situ hybridization , medicine , cancer research , gene , genetics , astrocytoma , genome , gene expression , chromosome

Glioblastomas are the most common and most malignant brain tumors in adults. A small subgroup of glioblastomas contains areas with histological features of oligodendroglial differentiation (GBMO). Our objective was to genetically characterize the oligodendroglial and the astrocytic parts of GBMOs and correlate morphologic and genetic features with clinical data.

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