Open AccessGlucagon-like peptide-1 receptor expression after myocardial infarction: Imaging study using 68Ga-NODAGA-exendin-4 positron emission tomography
Author(s) -
Mia Ståhle,
Ville Kytö,
Max Kiugel,
Heidi Liljenbäck,
Olli Metsälä,
Meeri Käkelä,
Xiangguo Li,
Vesa Oikonen,
Pekka Saukko,
Pirjo Nuutila,
Juhani Knuuti,
Anne Roivainen,
Antti Saraste
Publication year - 2020
Publication title -
journal of nuclear cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 82
eISSN - 1532-6551
pISSN - 1071-3581
DOI - 10.1007/s12350-018-01547-1
Subject(s) - medicine , positron emission tomography , myocardial infarction , glucagon like peptide 1 , ventricle , ligation , receptor , cd68 , immunohistochemistry , nuclear medicine , endocrinology , diabetes mellitus , type 2 diabetes
Activation of glucagon-like peptide-1 receptor (GLP-1R) signaling protects against cardiac dysfunction and remodeling after myocardial infarction (MI). The aim of the study was to evaluate 68 Ga-NODAGA-exendin-4 positron emission tomography (PET) for assessment of GLP-1R expression after MI in rats.